Ayurveda is the science of life. It is a comprehensive system of health care. The Fundamental concepts of Ayurveda are systematized in classical texts like Bruhatrayi and Laghutrayi. A Healthy skin (Twacha) is a source of pleasure not only to its owner but also to one who looks at it. Twacha regulates cellular and molecular interactions and governs many crucial responses to our environment. Because of its visibility Twacha reflects one’s emotions and some aspects of normal physiology. A slight change in its colour might be an indication towards the homeostatic imbalances in the body. Dosha Dhatu and Mala play a vital role in maintaining Twacha Swasthya .So in present article it is an attempt to study concept of Twacha and its relation with Dosha Dhatu and Mala.