In paediatric patients, neuropsychological diseases such as cerebral palsy are seen. In such cases, as these are asadhya diseases, only yapan is possible, using rasayana and medhya medications. Ghrit kalpana is majorly prescribed in such cases. However, children are reluctant to take sidhha ghrita due to disagreeable taste, texture and smell. Also ghrita kalpanas are comparatively costlier. An attempt was made to find an alternative which acts as medhya rasayana, and would be palatable for paediatric patients and also be cost-effective than sidhha ghrit. Kushmanda fruit (Benincasa hispida) exhibits medhya properties, and is sheet, brihan and chetorog hrut. Kushmandavaleha is balya, brihan along with having other benefits of kushmanda. Kushmandavaleha was administered to 3 paediatric patients suffering from cerebral palsy, Duchenne’s muscular dystrophy and having psychological symptoms such as krodhadhikya, rodan etc in dose 5gms twice a day. After 30 days, significant effect was seen on these symptoms. Kushmandavaleha can serve as an effective medhya rasayanaa which is economical and palatable in paediatric patients suffering from neuropsychological disorders.