Ageing is a process of physical, psychological and social change in multi dimensional aspect. Geriatric health care is very important .Sandhigata Vata i.e. osteoarthritis is also known as degenerative joint disease. Majority of geriatric population suffer from Sandhigata Vata. Modern medicine has limitation in treating Osteoarthritis and has many adverse effects with its prolonged use. Now in the era of TKR (Total Knee Joint Replacement) Surgery, but due to some underlying systemic illness, financial constrains it is not possible to opt for surgical intervention.. In Ayurveda it is mentioned that in Vardhakya Avastha all Dhatus undergo Kshay leading to Dhatukshayaj Vatprakopa Samprapti. In Sandhigata Vata there is Kshay of Asthidhatu. Bastichikitsa is considered to be Shreshtha(best) in Vata dosha Chikitsa. In the present case Panchatikta Ksheerbasti along with sarpi (Ghee)was given in the patient suffering from OA for 30days. Panchatikta Ksheerbasti showed symptomatically good result in Sandhigat Vata.