Aging of the skin is the result of continuous "wear and tear" processes. This study gives a case report of 35years married female patient with complaints of wrinkles formation in early age. This study was planned to evaluate the Role of Navan Nasya Karma as an anti-wrinkle treatment in ageing process. Navan Nasya was done by instilling drops of Yashtimadhukadi tail in the nostrils for 21 days. The improvement evaluation was done by Wrinkle Severity Rating Scale (WSRS).It was observed that before treatment the score was 4 and improvement was seen until score 2. Further studies may be conducted by taking more samples with more number of sittings.