Secondary infertility indicates previous pregnancy but failure to conceive subsequently. This condition can be correlated with sapraja in Ayurveda.[i] The incidence of sapraja is keep on increasing due to lifestyle changes , irregular menstrual cycle etc which leads to bijotsarga by misbalancing the doshas during rutuchakra. This case is an ideal example of sapraja and is successfully managed with ayurveda therapy. The patient was unable to conceive for 6 years after her first baby with the complaints of early irregular menses, poor appetite & sleep disturbance, constipation. Considering clinical features vata, kapha, artava involved in pathology. Patient was treated with virechana, kala basti & uttara basti followed by Garbhapal ras, chitrakadi vati and bijadharakyoga. During treatment, the patient got relief from signs and symptoms and got fruitful pregnancy. Hence it was concluded that above therapy is highly effective in the management of secondary infertility.