A single-arm clinical study of Shatavari Churna in Pitta Avritta Vyana Vayu w. s. r. to premenstrual syndrome

Abstract

Introduction: Premenstrual Syndrome is one of the major but underrated diseases of female physiology. Ignorance and ill-treatment may complicate it to a more severe form, premenstrual dysphoric disorder. Shatavari Churna is an ayurvedic herbal drug that has the potential to impact largely the female reproductive system. Here is an attempt to study the role of Shatavari Churna, especially in Premenstrual Syndrome.

Methods: The present study implemented an open-label, single-arm before and after a study conducted at Yashwant Charitable Hospital, by Yashwant Ayurved College Kodoli, Kolhapur with 100 individuals (who fulfilled the inclusion and diagnostic criteria). A random sampling technique was adopted for the study. The trial drug was given at the dose of 3 grams twice daily after food with water for 3 menstrual cycles. A predefined symptom scale was used to measure the efficacy before and after the treatment. Statistical analysis of subjective parameters was assessed using the Wilcoxon Signed rank test and McNemar test. In subjective parameters, statistical significance was obtained in Sarvanga Daha, Klama, Santapa & Vedana (P < 0.05).

Conclusion: The Shatavari Churna (3 grams twice daily after food with water for 3 menstrual cycles) is effective in the management of Pitta Avritta Vyana Vayu (Premenstrual syndrome) and requires further study like an animal study by using a more vigorous method.