Sushrutacharya is the pioneer of Ayurved Rachana Sharir and Ayurvedic Shalya Tantra. He has mentioned various concepts in Rachana Sharir in the Sushrut samhita sharirsthan. In 7th adhyaya of the sharirsthan, he has given the meticulous information regarding the Siras of the human body. In the same adhyaya the Acharya has named some Avedhya Siras which should not be punctured during the treatment aspect. The Lohitaksha sira is one of them. So, it is essential to know the details of this lohitaksha sira which is present in shakhapradesh (Both extremities). So, for this purpose, this study is to clarify the perception of Lohitaksha sira with the help of modern anatomy. Lohitaksha is also a marma which is vital spot in the human body. So, lohitaksha sira can be called as marmashrit sira.