Prakriti(nature) is the main concepts of ayurveda . It is the main factor as a diagnostic tool of disease,and plays an important role in the treatment of disease. According to the Principles of Ayurveda, the function of all bodies depends on the Prakriti. There is two types of Prakriti viz. Sharir and manas prakriti .This two plays an important role in hetu, linga, aushadha skandha. Vyadhi (disease)is the opposite condition of health.According to Shabdakalpadrum "Vyadhi" means 'Pain'. When adding the 'Ikarant' in vyadh that means "conglomeration the pain". According to the tridosha Siddhanta of the Ayurveda, there are Vata ,Pitta and Kapha dosahs are responsible for the Prakriti formation, as an imbalance in doshas leads to the diseases, therefore knowledge of Prakriti of an individual is essential for the knowledge of vikriti. Without the knowledge of an individual's Prakriti, it is practically impossible to apply ayurvedic fundamental principles in the promotion of health prevention as well as the management of diseases in a successful manner.