Background: Pippali, Piper longum (P.longum) usually called pippali which is a member of the Piperaceae family, is frequently used medicinal herb in Ayurved, Unani & Siddha system of medicine. In traditional medicine world it is being used to treat most of the systemic disorders. This systematic review was conducted with an objective to search, explore & compile the phytochemical constituents & their efficacies both in modern and traditional part to understand as a potential therapeutic agent. Material & method: Published details scientific literature on P. Longum by various research scholars, organizations & Pharmacopeias were reviewed. The review criterion was restricted to bio-efficacy and phyto-pharmacological activities of longum. Results and Conclusions: This review shows various experimental studies conducted on Bio-active compounds isolated from P. longum has prospective uses as anticancer, antilipidemic, antifungal and radioprotective.
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