Introduction: Yoga focuses harmony between mind and body. To achieve this, Yoga uses movements, breath, posture, relaxation and meditation order to establish a healthy, lively and balanced approach to life. Today’s sedentary lifestyle there is lots of problems related to musculoskeletal system. Aasana is a part of Ashtangyoga can give solution to this problems by keeping the body strong and balanced. Yoga Aasana can help redress problems associated with poor body posture and structural decay. Aasana practices have positive effect on the musculoskeletal system. Aim:To study the effect of Aasana in Musculosketal system – a literary study. Objective: To create awareness among society about Yoga Aasana. Discussion and Conclusion: Role of Yoga Aasana in daily life is keeping one’s body in perfect shape and mind in perfect condition. It also improves practitioner’s steadiness, stamina, flexibility, endurance, neuromuscular co-ordination.